Cinnarizine
AntihistamineUses of Cinnarizine
Cinnarizine is used to relieve dizziness, nausea, and vomiting caused by inner ear disturbances and balance disorders.
Cinnarizine is commonly used for:
- Motion sickness: Prevents and relieves nausea and vomiting triggered by travel by sea, air, or road.
- Vertigo: Reduces the sensation of spinning or dizziness caused by inner ear disorders.
- Ménière's disease: Helps manage symptoms including severe dizziness (vertigo), nausea, ringing in the ears (tinnitus), and a feeling of pressure or fullness in the ear.
- Labyrinthitis and vestibular neuritis: Eases dizziness and balance problems caused by inflammation of the inner ear.
- Balance-related symptoms associated with certain vestibular disorders: Assists in managing dizziness and balance problems.
- Inner ear circulation disorders: May help reduce symptoms such as dizziness and tinnitus associated with impaired blood flow to the inner ear.
Side effects of Cinnarizine
- Drowsiness
- Stomach upset
How Cinnarizine works
- Cinnarizine works primarily by blocking calcium channels in the smooth muscle cells of blood vessels supplying the inner ear and may help improve blood flow in this area.
- By improving blood flow to the inner ear, Cinnarizine helps restore normal function to the balance organs, which reduces symptoms such as dizziness, vertigo, nausea, and vomiting.
- Cinnarizine also has antihistamine properties, meaning it blocks histamine H1 receptors. Histamine is involved in triggering nausea and vomiting, particularly in response to movement or inner ear disturbances. By blocking these receptors, Cinnarizine helps suppress the signals from the inner ear to the brain's vomiting centre, reducing the urge to vomit and the sensation of dizziness.
- Together, these two actions make Cinnarizine effective for both treating active episodes of vertigo and preventing motion sickness.
Certified content
Written By
Dr. Sachin SinghMedical Team Lead & Reviewer| 7 years
MBBS
Reviewed By
Dr. Mandeep ChadhaLead Medical Content Reviewer| 12 years
MBBS, DNB (OBGY)
Expert Advice
Dosage Forms Available
- This medicine is available in tablet and capsule form and can be taken via oral route.
Age and Dose Restrictions
- This medicine should be used in children above five years of age.
Contraindications
- This medicine is contraindicated in patients allergic to cinnarizine, having porphyria, or Parkinson's disease.
Other Medications To Avoid With This Medicine
- Avoid taking antidepressants (amitryptiline) or other sedatives with this medicine.
Overdose and Missed Dose
- Taking more than the prescribed dose of Cinnarizine may cause symptoms such as excessive drowsiness, low blood pressure, tremor, and involuntary muscle movements. In severe cases, seizures may occur. If you suspect an overdose, seek emergency medical attention immediately. Strict adherence to the prescribed dose is essential.
- If you miss a dose of Cinnarizine, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to compensate for the one you missed.
Management Of Side Effects
- Take this medicine with food to reduce gastrointestinal side effects and continue taking it as prescribed. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.
Use In Driving And Operating Machinery
- This medicine can cause drowsiness. It is not recommended to drive, operate machinery, or do other activities that require mental alertness or coordination after taking this medicine.
Use in Pregnancy and Lactation
- This medicine is not recommended during pregnancy and breastfeeding women.
Caution in Other Conditions
- Caution is advised in older adults and patients with liver and kidney impairment.
- This medicine may cause drowsiness. Do not drive or use machines after taking this medicine, as these activities require focus and attention.
Special Dietary & Lifestyle Recommendation
- Avoid consuming alcohol with this medication to avoid worsening of the side effects of this medication.
- It is recommended to avoid consuming food right before travelling to minimise the likelihood of vomiting during the journey.
- To alleviate nausea, vomiting, and ear ringing, ensure that you have sufficient airflow during travel.
Frequently asked questions
1. Is it safe to take Cinnarizine during pregnancy?
No, this medication is not recommended to be used during pregnancy.
2. Is it safe to take Cinnarizine while breastfeeding?
No, this medication is not recommended to be used while breastfeeding.
3. What are the precautions and warnings to be followed while taking Cinnarizine?
This medicine should not be used in patients who are allergic to this medicine or patients having porphyria or Parkinson’s.
4. Is this medication safe for liver disease?
No, this medicine is not recommended for patients with liver diseases.
5. Is this medication safe for kidney disease?
No, this medication is not recommended for patients with kidney diseases.
6. What is Cinnarizine used for?
Cinnarizine is used to prevent and treat motion sickness, vertigo, and balance disorders. It improves blood flow in the inner ear, reducing symptoms like nausea, dizziness, and vomiting. It is also helpful for managing conditions causing dizziness, such as Meniere’s disease.
Cinnarizine in other salts
List of medicines for Cinnarizine
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