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Cilnidipine

Antihypertensive

Uses of Cilnidipine

Cilnidipine is used to manage high blood pressure (hypertension). It helps relax and widen blood vessels, making it easier for the heart to pump blood and may help reduce the risk of complications such as stroke and other cardiovascular problems.

Cilnidipine is commonly used for:

  • High blood pressure (hypertension): Reduces elevated blood pressure by relaxing the walls of blood vessels, improving blood flow throughout the body.
  • Chronic stable angina: Helps relieve chest tightness caused by reduced blood supply to the heart by widening the coronary arteries.
  • Hypertension with kidney involvement: Particularly useful in patients with high blood pressure and early kidney disease, as it may help reduce protein loss in urine.
  • Hypertension with heart rate concerns: Unlike some other calcium channel blockers, Cilnidipine may cause less increase in heart rate, making it suitable for certain patients.

Side effects of Cilnidipine

The side effects of Cilnidipine are:

  • Fatigue 
  • Ankle swelling
  • Sleepiness
  • Flushing
  • Hypotension 
  • Headache
  • Nausea
  • Dizziness
  • Palpitations 
  • Oedema 
  • Abdominal pain

How Cilnidipine works

  • Cilnidipine works by blocking the entry of calcium into blood vessel walls and nerve endings, which causes blood vessels to relax and widen.
  • It belongs to a group of medicines called calcium channel blockers, specifically the dihydropyridine type. Calcium is needed for blood vessels to contract. By blocking calcium channels, Cilnidipine causes the smooth muscle in blood vessel walls to relax, reducing resistance and lowering blood pressure.
  • What sets Cilnidipine apart from older calcium channel blockers is that it blocks both L-type and N-type calcium channels. L-type channels control blood vessel constriction, while N-type channels are found in nerve endings and influence the release of certain hormones that raise blood pressure. By blocking both, Cilnidipine provides longer-lasting blood pressure control and may be associated with a lower incidence of certain side effects, such as ankle swelling and reflex increases in heart rate, compared with some other medicines in this class.

Certified content

Written By

docImg
Dr. Sachin SinghMedical Team Lead & Reviewer| 7 years

MBBS

Reviewed By

Dr. Mandeep Chadha
Dr. Mandeep ChadhaLead Medical Content Reviewer| 12 years

MBBS, DNB (OBGY)

Expert Advice

Dosage Forms Available

  • Cilnidipine is available for use via the oral route (tablet and an extended-release (long-acting) capsule).

Age and Dose Restrictions

  • This medicine is meant for adults and children above 18 years of age.

Contraindications

  • Cilnidipine is contraindicated in patients with known allergies to cilnidipine, severe heart issues, bronchial asthma or related bronchospastic conditions, and sick sinus syndrome.

Other Medications To Avoid With This Medicine

  • It is advised against utilising any antiarrhythmic agents (e.g., quinidine), antiepileptic medications (such as phenytoin), antituberculosis treatments (like rifampicin), antibiotics (including erythromycin), other antihypertensive tablets (such as amlodipine), and antipsychotic medications with this medication. Before initiating any prescription or over-the-counter medications, consultation with a doctor is imperative.

Overdose and Missed Dose

  • An overdose of Cilnidipine may cause a significant drop in blood pressure, leading to symptoms such as dizziness, fainting, headache, flushing, confusion, and an irregular or fast heartbeat. If you suspect an overdose, seek emergency medical attention immediately.
  • If you miss a dose of Cilnidipine, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for the missed one. Consistent daily use is important for effective blood pressure control.

Management of Side Effects

  • To manage the side effects of Cilnidipine, it's essential to stay well-hydrated and avoid sudden position changes to reduce dizziness and hypotension. Light meals and rest ease nausea, fatigue, and sleepiness. Elevating the legs can minimise ankle swelling and oedema. If palpitations or abdominal pain persist, consult your doctor for dosage adjustment or alternative treatment.

Use In Driving And Operating Machinery

  • This medicine can affect your ability to drive or operate heavy machinery.

Use in Pregnancy and Lactation

  • Cilnidipine is not recommended during pregnancy or breastfeeding.

Cautions in other conditions

  • Exercise caution when using Cilnidipine if you have hypotension, heart failure, or other heart conditions​. Elderly patients should use this medication cautiously due to the increased risk of side effects.​

Special Dietary & Lifestyle Recommendation

  • Avoid alcohol when you are taking Cilnidipine.
  • Cilnidipine can be taken with or without meals.
  • People diagnosed with hypertension and coronary artery disease are encouraged to adopt lifestyle adjustments, incorporating dietary modifications such as adhering to a low-sodium, low-carbohydrate, and low-fat diet. Additionally, engaging in exercise, such as brisk walking for a minimum of thirty minutes daily, five days a week is advisable to manage blood pressure effectively.
  • Individuals with hypertension face a persistent risk of heart attacks and strokes. Therefore, it is crucial to establish a routine for blood pressure monitoring, either through the use of a digital blood pressure monitoring device at home or through regular visits to the doctor.
  • Thorough education regarding the identification of signs and symptoms linked with heart attacks and strokes is imperative. This understanding can facilitate prompt interventions, reducing complications and fostering a swifter and more comprehensive recovery.

Frequently asked questions

This medicine starts showing its effects within a few hours after consumption.

Avoid usage if you experience an allergic reaction (hypersensitivity) to Cilnidipine. It is advisable to seek advice from a doctor promptly.

Do not stop taking this medication without consulting your doctor, even if you feel healthy.

Consult your doctor before taking this medicine if you have kidney or liver issues to ensure its safety and proper dosage.

No, this medicine does not affect contraception.

Both Amlodipine and Cilnidipine are effective antihypertensive drugs. Cilnidipine has a slight advantage over Amlodipine in reducing heart rate and pulse rate.

Cilnidipine is probably safe for use in patients with kidney disease. Consult your doctor for personalized advice.

Cilnidipine efficacy is regardless of administration time, but bedtime dosing reduces nocturnal blood pressure and is useful for patients with uncontrollable morning hypertension. Consider taking it at the same time each day.

Maintain a healthy weight, exercise regularly, and follow a heart-healthy diet. Limit salt, alcohol, and stress, and prioritise good sleep.

Cilnidipine is a medicine used to treat angina (chest pain) and high blood pressure (hypertension).

Cilnidipine is used to treat high blood pressure (hypertension) by relaxing blood vessels to improve blood flow, which reduces the workload on the heart. This helps lower the risk of heart-related complications like stroke and heart attack, while also protecting the heart.

Terms & Conditions


List of medicines for Cilnidipine

Cilacar 20 Tablet 15
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Cilacar 10 Tablet 15
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Cilogard 10 Tablet 10
Cilogard 10 Tablet 10
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Dilnip 10 Tablet 15
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₹197.88
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Cinaloc 10 Tablet 10
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₹85.92
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Nexovas 10 Tablet 15
Nexovas 10 Tablet 15
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₹170.13
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Cilaheart 10 Tablet 15
Cilaheart 10 Tablet 15
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₹132.3
MRP ₹174.08
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Cilacar 5 Tablet 15
Cilacar 5 Tablet 15
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₹116.26
MRP ₹145.32
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