The main use of Aspirin + Isosorbide-5-Mononitrate / Isosorbide Mononitrate is for the prevention and management of angina pectoris due to coronary artery disease. This combination medication belongs to the class of antiplatelet agents and vasodilators.
It is also indicated for reducing the risk of death and myocardial infarction in patients with a history of heart attack or unstable angina, and for reducing the risk of death and recurrent stroke in patients who have had an ischemic stroke or transient ischemic attack.
Headache
Dizziness
Nausea and vomiting
Stomach pain or discomfort
Heartburn
Aspirin + Isosorbide-5-Mononitrate / Isosorbide Mononitrate is an antiplatelet and vasodilator combination.
Aspirin, the first component, is an antiplatelet agent. It inhibits the production of prostaglandins, which are substances that promote inflammation, pain, and fever. This reduction in prostaglandin synthesis helps prevent the formation of blood clots, thereby decreasing the risk of heart attacks and strokes.
Isosorbide Mononitrate, the second component, is a vasodilator belonging to a group of medicines known as nitrates. It works by relaxing and widening blood vessels. This improves the flow of blood to the heart and reduces the workload on the heart muscle, thereby helping to prevent angina attacks.
Doctor of Medicine
BMS, FMC, MD Resident
Aspirin + Isosorbide-5-Mononitrate / Isosorbide Mononitrate is available for use in the form of oral tablets.
This combination medication is generally recommended for adults. It may also be used in adolescents and children, but only under the close supervision of a doctor.
Aspirin + Isosorbide-5-Mononitrate / Isosorbide Mononitrate is contraindicated in patients with known allergies to either aspirin or isosorbide mononitrate.
The use of this medication is also contraindicated in patients with active peptic ulcer disease, severe liver impairment, severe kidney impairment, low blood pressure, and decreased blood volume.
Aspirin + Isosorbide-5-Mononitrate / Isosorbide Mononitrate may interact with blood thinners (such as warfarin, heparin), other antiplatelet agents (like clopidogrel, ticlopidine), nonsteroidal anti-inflammatory drugs (NSAIDs like ibuprofen)
Before starting any new prescription medicine or over-the-counter medicine, please consult your doctor.
An overdose of Aspirin + Isosorbide-5-Mononitrate / Isosorbide Mononitrate can lead to symptoms such as ringing in the ears, rapid or deep breathing, fever, confusion, seizures, and coma. In such a case, seek immediate medical attention.
If you happen to miss a dose of this medicine, take it as soon as you remember. However, if it is nearly time for the next dose, skip the missed dose and continue with your regular dosing schedule.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water can help manage some of the gastrointestinal side effects such as nausea and stomach pain.
To manage the side effect of dizziness, it is advised to rise slowly from a sitting or lying position.
Aspirin + Isosorbide-5-Mononitrate / Isosorbide Mononitrate can cause dizziness or light-headedness. Therefore, avoid driving or operating heavy machinery until you know how this medicine affects you.
Aspirin + Isosorbide-5-Mononitrate / Isosorbide Mononitrate should be used during pregnancy only if clearly needed and under the supervision of a doctor.
As aspirin is excreted in breast milk, breastfeeding while taking this medication is not recommended.
Patients with severe anaemia, hyperthyroidism, and glaucoma should use Aspirin + Isosorbide-5-Mononitrate / Isosorbide Mononitrate with caution.
Following a balanced diet rich in fruits, vegetables, whole grains, lean proteins and low-fat dairy can help in managing angina pectoris due to coronary artery disease.
Quitting smoking and restricting alcohol intake can lower risk factors associated with heart disease.
Regular physical activity can help keep your heart healthy. However, it's essential to talk to your doctor about the type and amount of exercise that is suitable for you.
Stress management is crucial as stress can trigger angina pain. Relaxation techniques such as deep breathing, yoga, and meditation can help manage stress levels.
Regular check-ups and following the medication plan as prescribed by the doctor is crucial for managing the underlying disease effectively.
Frequently asked questions
Yes, there are no animal-derived components in Aspirin + Isosorbide-5-Mononitrate / Isosorbide Mononitrate. However, it is always advisable to consult your doctor for specific concerns related to dietary restrictions and medicine intake.
There are no specific reports indicating that Aspirin + Isosorbide-5-Mononitrate / Isosorbide Mononitrate leads to mood changes. However, if you experience any unusual mood swings or changes in behaviour while taking this medicine, you should inform your doctor promptly.
The duration of use of Aspirin + Isosorbide-5-Mononitrate / Isosorbide Mononitrate depends on the severity of the condition and the patient's overall health status. It is essential to follow your doctor's advice regarding the duration of treatment.
There is no direct evidence to suggest that Aspirin + Isosorbide-5-Mononitrate / Isosorbide Mononitrate affects menstruation. If you notice any irregularities or changes in your menstrual cycle while taking this medicine, please consult your doctor.
There are no known natural substitutes for prescribed medications like Aspirin + Isosorbide-5-Mononitrate / Isosorbide Mononitrate.
No, Aspirin + Isosorbide-5-Mononitrate / Isosorbide Mononitrate is not known to cause dependency or addiction. It should be taken as prescribed by your doctor to manage your condition effectively.
Aspirin + Isosorbide-5-mononitrate / Isosorbide Mononitrate in other salts
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