Acebrophylline + Guaifenesin + Terbutaline is mainly used to manage symptoms associated with chronic respiratory conditions such as asthma, chronic bronchitis, and emphysema. It falls under the category of bronchodilators and expectorants.
Additionally, it helps in reducing chest tightness, wheezing, difficulty breathing, and making coughs more productive by loosening phlegm.
Nausea
Vomiting
Abdominal pain
Diarrhoea or constipation
Dizziness or drowsiness
Acebrophylline + Guaifenesin + Terbutaline is a combination medication composed of a bronchodilator and two expectorants.
Acebrophylline, the bronchodilator in the mix, inhibits phosphodiesterase enzymes. This inhibition leads to the relaxation of bronchial smooth muscle and stimulates bronchial cells to secrete surfactant, a substance that reduces surface tension and helps clear mucus.
Guaifenesin, an expectorant, works by drawing water into the bronchi, which decreases the thickness of secretions. This action not only lubricates the irritated respiratory tract but also promotes the expulsion of mucus.
Terbutaline, an expectorant and a bronchodilator as well, activates beta-2 adrenergic receptors on airway smooth muscle cells. This activation leads to muscle relaxation and bronchodilation, widening the airways for easier breathing. It also inhibits the release of agents that can constrict the bronchi from mast cells.
Doctor of Medicine
BMS, FMC, MD Resident
Acebrophylline + Guaifenesin + Terbutaline can be taken orally (tablet, syrup, capsule and effervescent granule).
This medicine is usually recommended for adults, and children under 12 years of age should avoid using it unless advised by a doctor.
This medicine should be avoided by people with a known hypersensitivity or allergy to any of the components: Acebrophylline, Guaifenesin, or Terbutaline.
It is also contraindicated for patients suffering from acute asthma attacks.
Acebrophylline + Guaifenesin + Terbutaline may interact with other bronchodilators (such as salbutamol), decongestants (like pseudoephedrine), beta blockers (such as propranolol), MAO inhibitors (like selegiline), tricyclic antidepressants (like amitriptyline), diuretics (like furosemide) and other medications that affect heart rhythm (such as digoxin).
Overdosing on this medication can lead to increased heart rate, tremors, and, in severe cases, an irregular heartbeat. If you suspect that you have taken an overdose, inform your doctor immediately.
If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosage schedule.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening symptoms, please consult your doctor.
To manage nausea and vomiting, try taking the medication with a light meal or snack.
Dizziness can sometimes be managed by getting up slowly from a sitting or lying position.
If you experience nervousness, practising relaxation techniques like deep breathing exercises may help.
This medication may cause dizziness or drowsiness in some individuals. If you experience these side effects, avoid driving or operating heavy machinery.
This combination medicine should only be used during pregnancy or lactation if prescribed by your doctor.
Patients with heart diseases, high blood pressure, diabetes, glaucoma, or seizure disorders should use this medicine with caution as it can exacerbate these conditions.
Use with caution in patients with renal or hepatic impairment as it can affect the metabolism and excretion of the medicine.
It is advisable to avoid foods that trigger asthma and bronchitis symptoms, such as dairy products, processed foods, and foods rich in histamine.
It is beneficial to maintain a healthy weight as obesity can worsen breathing problems.
Regular gentle exercise like walking or yoga can help strengthen the respiratory system.
Managing stress through mindfulness techniques or talking therapy can also help as stress can trigger asthma attacks.
Frequently asked questions
There is no specific food interaction for this combination medication. However, taking it with a meal can help minimise potential gastrointestinal side effects like nausea and stomach pain.
Acebrophylline + Guaifenesin + Terbutaline is usually prescribed by a doctor and is not typically available over the counter.
No, Acebrophylline + Guaifenesin + Terbutaline does not contain steroids.
Acebrophylline + Guaifenesin + Terbutaline is not directly associated with affecting weight gain. However, if you experience sudden weight changes while taking this medication, it's important to discuss this with your doctor.
This medication can cause gastrointestinal side effects such as nausea and stomach pain. Taking it with meals can help minimise these side effects.
As none of the constituents of this combination are categorised as sulfa medicines, it may be safe for individuals with a sulfa allergy.
While vitamins generally do not interfere with this medication, some supplements may interact with other medications or health conditions. Always discuss with your doctor before starting any new supplements.
Acebrophylline + Guaifenesin + Terbutaline in other salts
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