Warfarin

Dosage Forms Available

• Warfarin can be taken orally (tablet).

Age and Dose Restrictions

• This medication is suitable for use by adults aged 18 and above.

Contraindications

• This medication is contraindicated in patients with known allergies to Warfarin. It is also contraindicated in patients with active bleeding, severe liver or kidney disease, uncontrolled hypertension, and patients who have recently had a stroke, aneurysm, or bleeding in the brain.

Other Medications to Avoid

• Warfarin may interact with salicylates (such as aspirin), NSAIDs (like ibuprofen and naproxen), antibiotics (such as ciprofloxacin and erythromycin) and anticonvulsants (such as carbamazepine).

Overdose and Missed Dose

• An overdose of Warfarin can be life-threatening due to the increased risk of serious bleeding. If you suspect an overdose, seek immediate medical attention.

• If you miss a dose of Warfarin, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• If you experience mild to moderate bleeding (such as nosebleeds or gum bleeding), applying pressure to the area may help.

• If you experience nausea or vomiting, taking this medicine with food can help.

• If you experience mild diarrhoea, ensure you stay hydrated by drinking plenty of fluids.

Use in Driving and Operating Machinery

• Warfarin does not generally affect your ability to drive or operate heavy machinery. However, if you experience side effects like dizziness or fainting, avoid these activities.

Use in Pregnancy and Lactation

• Warfarin can cause fetal harm and is contraindicated in pregnancy except in women with mechanical heart valves at high risk of thromboembolism.

Caution in Other Conditions

• Patients with liver disease or kidney disease should use Warfarin with caution, as the medication is metabolised by the liver and eliminated by the kidneys. Individuals with a history of bleeding disorders should also exercise caution when using Warfarin due to the increased risk of bleeding.

Special Dietary and Lifestyle Recommendations

• Maintain a consistent intake of vitamin K, as sudden changes can affect how Warfarin works in your body. Foods that are high in vitamin K include green leafy vegetables like kale and spinach.

• Avoid activities that can increase your risk of bleeding or injury. Use caution with sharp objects like razors and nail cutters.