Home/Drugs By Ailments / Pheniramine

Pheniramine

Uses of Pheniramine

Pheniramine is a first-generation antihistamine used to relieve allergy symptoms affecting the nose, eyes, and skin.

Pheniramine is commonly used for:

• Allergic rhinitis (hay fever): Reduces sneezing, a runny or blocked nose, and itchy, watery eyes caused by seasonal pollen or year-round allergens such as dust and pet dander.
• Urticaria (hives): Relieves skin itching, redness, and raised welts caused by allergic reactions.
• Allergic conjunctivitis: Eases itching, watering, and redness of the eyes triggered by allergens.
• Angioedema: Helps reduce localised swelling beneath the skin associated with allergic reactions.
• Eczema and dermatitis: Provides relief from itching associated with allergic skin conditions.
• Common cold and flu symptoms: Reduces nasal discharge, sneezing, and throat irritation that accompanies cold and flu infections.
• Motion sickness: Used to prevent and relieve nausea and dizziness associated with travel.
• Meniere's disease: May help manage vertigo, tinnitus, and balance disturbances in inner ear disorders.

Side effects of Pheniramine

  • Drowsiness

  • Dry mouth, nose, and throat

  • Dizziness

  • Headache

  • Nausea and vomiting

How Pheniramine works

  • Pheniramine works by blocking histamine H1 receptors throughout the body, which prevents histamine from triggering allergic symptoms.
  • When the body encounters an allergen such as pollen, dust, or pet dander, the immune system releases a chemical called histamine. Histamine binds to H1 receptors in the nose, eyes, skin, and airways, causing inflammation, itching, increased mucus production, and watery eyes.
  • Pheniramine competes with histamine for these H1 receptors, blocking histamine from attaching and activating them. This prevents or reduces the allergic response, relieving symptoms such as sneezing, a runny nose, itching, and watery eyes.
  • As a first-generation antihistamine, Pheniramine can cross into the brain, which may cause drowsiness. This sedative effect can sometimes be useful in managing itching that disrupts sleep, but it also means care should be taken when driving or operating machinery.

Certified content

Written By

docImg
Dr. Michelle FrankMedical Content Writer| 10 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi RoshaMedical Content Writer| 10 years

BAMS, FMC, MD Resident

Expert Advice

Dosage Forms Available:

  • Pheniramine is available in several different forms. It can be taken orally (tablets and syrup) and intravenously (injection).

Age and Dose Restrictions:

  • Typically, Pheniramine is prescribed for adults and children over the age of 2 years. It is not recommended for use in children under 2 years without first consulting a paediatrician.
  • The dosage of Pheniramine will depend on various factors such as your age, weight, and overall health condition. Follow your doctor's instructions or the directions on the product label.

Contraindications:

  • You should not take this medication if you have a known allergy to Pheniramine. This medicine should be avoided by those with severe liver or kidney disease and those suffering from narrow-angle glaucoma, urinary retention, or peptic ulcer disease.

Other Medications to Avoid:

  • Pheniramine may interact with central nervous system depressants (diazepam), monoamine oxidase inhibitors (like isocarboxazid and phenelzine), and anticholinergic medications (e.g., atropine and scopolamine).

Overdose and Missed Dose:

  • An overdose of Pheniramine may cause extreme drowsiness, dry mouth, dilated pupils, flushing, rapid heartbeat, agitation, confusion, and in severe cases, seizures or loss of consciousness. These symptoms require immediate medical attention. If you suspect an overdose, contact your doctor or go to the nearest hospital immediately. Strict adherence to the prescribed dose is essential.
  • If you miss a dose of Pheniramine, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at the same time to make up for the missed one.

Management of Side Effects:

Most side effects are temporary and generally harmless and resolve upon discontinuation of this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If you experience drowsiness or sedation after taking this medication, try taking it at bedtime to help minimise these effects.
  • Drinking plenty of water may help to alleviate dry mouth. Additionally, sucking on sugarless candy or ice chips may help to keep your mouth moist.
  • If you experience constipation, increasing your intake of fibre and water may help.

Use in Driving and Operating Machinery:

  • This medication may affect your ability to drive or operate heavy machinery. If you feel dizzy or drowsy after taking Pheniramine, you should avoid these activities until the effects wear off.

Use in Pregnancy and Lactation:

  • Pheniramine should only be used during pregnancy or while breastfeeding if your doctor determines that the benefits outweigh the risks. Always consult your doctor before taking any medication during pregnancy and breastfeeding.

Caution in Other Conditions:

  • If you have a history of asthma, glaucoma, enlarged prostate, or urinary retention, you should exercise caution when taking Pheniramine as it may worsen these conditions. Inform your doctor of any existing medical conditions before starting a new medication.

Special Dietary and Lifestyle Recommendations:

  • It is crucial to understand the allergic trigger (pollen, furs, or food). You can undertake an allergy test as well. Avoid these triggers to stay healthy.
  • Have a diet rich in vitamin C, and incorporate a healthy portion of fresh fruits and vegetables with every meal.

Frequently asked questions

Yes, Pheniramine can be taken with or without food. If it causes an upset stomach, taking it with food may help alleviate this side effect.

Pheniramine typically starts working within 30 minutes to an hour after administration. The effects usually last for about 4 to 6 hours.

Pheniramine should not be used in children under the age of 2 years without consulting a paediatrician. For older children, always follow the dosage instructions provided by the doctor.

Consuming alcohol while taking Pheniramine is not recommended. Alcohol can increase the risk of drowsiness and impair cognitive function.

Pheniramine is an antihistamine that inhibits the effects of natural chemical histamine in the body like sneezing, itching, watery eyes, and a runny nose. Phenylephrine is a decongestant that constricts blood vessels in the nasal passages.

Pheniramine is a first-generation antihistamine in the alkylamine class, like brompheniramine and chlorpheniramine. It is used in several over-the-counter allergy and cold/flu treatments, along with other medications.

Taking cetirizine with chlorpheniramine may exacerbate adverse symptoms such as dizziness, drowsiness, and problems concentrating. Older people may suffer from impaired thinking, judgment, and motor coordination.

Pheniramine is an anti-allergic medicine used to relieve symptoms of allergies and the common cold. It helps reduce sneezing, runny nose, itchy or watery eyes, skin rashes, and swelling. It is commonly used for hay fever, hives, seasonal allergies, eczema-related itching, and other allergic reactions. Pheniramine provides fast relief, helping you feel more comfortable by easing allergy symptoms.

Terms & Conditions

List of medicines for Pheniramine

Avil 50 Tablet 15
Avil 50 Tablet 15
Sanofi India Ltd.
Pack of 15 Units
₹6.82
MRP ₹8.53
20% OFF
Intavil 25 MG Injection 10 ML
Intavil 25 MG Injection 10 ML
Intas Pharmaceuticals Ltd
Pack of 10 ML
₹49.48
MRP ₹61.85
20% OFF
Intavil 25 MG Injection 2 ML
Intavil 25 MG Injection 2 ML
Intas Pharmaceuticals Ltd
Pack of 2 ML
₹3.75
MRP ₹7.5
50% OFF
Avil Injection 2ml
Avil Injection 2ml
Sanofi India Ltd.
Pack of 2 ML
₹4.25
MRP ₹5.31
20% OFF
Eralet 25mg Tablet 15
Eralet 25mg Tablet 15
Maxzimaa Pharma Pvt. Ltd
Pack of 15 Units
₹14.25
MRP ₹17.81
20% OFF
Eralet 50mg Tablet 15
Eralet 50mg Tablet 15
Maxzimaa Pharma Pvt. Ltd
Pack of 15 Units
₹16.5
MRP ₹20.62
20% OFF
Cosavil 12.5/500 MG Tablet 10
Cosavil 12.5/500 MG Tablet 10
Sanofi India Ltd.
Pack of 10 Units
₹14.2
MRP ₹17.75
20% OFF

Subscribe

Claim your complimentary health and fitness tips subscription and stay updated on our newest promotions.

Registered Office Address

Intellihealth Solutions Private Limited
Unit-301 & 304, Lightbridge Tunga Village, Saki Vihar Rd, Chandivali, Powai, Mumbai, Maharashtra, India, 400072.
CIN: U62099MH2019PTC320566
Telephone:09240250346

Grievance Officer

Name: Kishor Kumar

Download Truemeds

Manage your health with ease Download Truemeds today!Get easy access to medicine refills, health information, and more. With our app, you'll never have to wait in line again. Download now and start taking control of your health.
Playstore
Apple App  Store

Contact Us

Our customer representative team is available 7 days a week from 9 am - 9 pm.


v4.28.1

copyright

2026 - Truemeds | All rights reserved. Our content is for informational purposes only. See additional information.

Trust Certified

Our Payment Partners

paymentPartnerpaymentPartnerpaymentPartnerpaymentPartner
paymentPartnerpaymentPartnerpaymentPartnerpaymentPartner