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Ofloxacin + Tinidazole

Uses of Ofloxacin + Tinidazole

  • Ofloxacin + Tinidazole is primarily used to manage certain bacterial and parasitic infections and belongs to the group of fluoroquinolone and nitroimidazole antibiotics.

  • It is also effective in managing bacterial infections of the urinary tract, kidneys, prostate, genital organs, lungs, airways, skin, bones, joints, and soft tissues. Additionally, it can be used for managing pelvic inflammatory disease, intra-abdominal infections, infectious diarrhoea caused by susceptible bacteria, and parasitic infections such as trichomoniasis, giardiasis and amebiasis.

Side effects of Ofloxacin + Tinidazole

  • Nausea

  • Vomiting

  • Diarrhoea

  • Abdominal pain

  • Dizziness

How Ofloxacin + Tinidazole works

  • Ofloxacin, the first component, belongs to the class of antibiotics called fluoroquinolones. It works by blocking the action of two important bacterial enzymes, DNA gyrase and topoisomerase IV. These enzymes are vital for bacteria to replicate and repair their DNA. By inhibiting these enzymes, Ofloxacin stops the multiplication of bacteria.

  • Tinidazole, the other active ingredient in this combination, is a nitroimidazole antibiotic. It works by directly damaging the DNA of harmful bacteria and certain protozoa, which leads to their death. It specifically targets anaerobic bacteria and protozoa.

Certified content

Written By

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Dr Vatsalya D GhanekarMedical Content Writer| 5 years

MD Ayurveda

Reviewed By

Dr. Osama Ahmed
Dr. Osama AhmedDental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Expert Advice

Dosage Forms Available

  • Ofloxacin + Tinidazole can be taken orally (tablet).

Age and Dose Restrictions

  • This combination medicine is meant for adults and children above 12 years of age.

Contraindications

  • Ofloxacin + Tinidazole is contraindicated in patients with known allergy to ofloxacin, tinidazole, or any other quinolone or nitroimidazole antibiotics. It is also contraindicated in patients taking tizanidine.

Other Medications to Avoid

  • Ofloxacin + Tinidazole may interact with antacids, iron, calcium and other metal cation containing products (such as multivitamin tablets), blood thinners (such as warfarin), antidiabetic agents (like metformin and insulin), nonsteroidal anti-inflammatory medicines (like ibuprofen and naproxen), respiratory medications (like theophylline), and immunosuppressants (like cyclosporine).

Overdose and Missed Dose

  • Overdose of Ofloxacin + Tinidazole may lead to severe adverse reactions such as confusion, drowsiness, dizziness, nausea, vomiting, tremors and seizures. In such cases, immediate medical attention is required.

  • If you miss a dose of Ofloxacin + Tinidazole, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and take your next dose at the scheduled time.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage nausea or vomiting, try taking this medicine with or after a meal.

  • To manage headache or dizziness, avoid sudden changes in posture and stay hydrated.

  • In case of genital itching or discharge, maintain good personal hygiene.

Use in Driving and Operating Machinery

  • Ofloxacin + Tinidazole may cause side effects like dizziness, confusion or hallucinations that can affect your ability to drive or operate machinery. Avoid such activities if you experience these side effects.

Use in Pregnancy and Lactation

  • Ofloxacin + Tinidazole is not recommended for use during pregnancy or while breastfeeding unless recommended by your doctor. Always consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding.

Caution in Other Conditions

  • Patients with a history of tendinitis, tendon rupture, myasthenia gravis, peripheral neuropathy or central nervous system disorders should exercise caution when taking Ofloxacin + Tinidazole.

  • Caution is also advised in patients with a history of serious allergic reactions or liver damage.

Special Dietary and Lifestyle Recommendations

  • Regular hand washing and practising good personal hygiene can help prevent the spread of bacterial infections.

  • Avoiding close contact with people who are sick can also help prevent infections.

  • If you have been prescribed Ofloxacin + Tinidazole for a digestive tract infection, it may be beneficial to include probiotics in your diet to restore the balance of healthy bacteria in your gut.

Frequently asked questions

Some central nervous system side effects like anxiety and confusion have been reported. If you notice any unusual emotional effects, it is wise to consult your doctor.

While some natural remedies may offer certain health benefits, they should not be used as a substitute for prescribed antibiotics like Ofloxacin + Tinidazole. Antibiotics are necessary to effectively manage bacterial and parasitic infections. Always consult your doctor before trying any alternative remedies.

The half-lives of ofloxacin and tinidazole are approximately 5-8 hours and 12-14 hours, respectively. Thus, both these substances should be mostly eliminated from your body within 2-3 days after the last dose. However, individual factors like age, health status, and metabolism can affect this time frame.

No! However, if you experience any irregular menstruation or other unusual symptoms while taking this medicine, consult your doctor.

Though appetite changes are not listed as common side effects of Ofloxacin + Tinidazole, individual reactions can vary. If you notice a significant change in your appetite while taking this medicine, consult your doctor.

The active ingredients in Ofloxacin + Tinidazole itself are not derived from animal sources. However, the capsule or tablet form might contain components derived from animals. If you are vegetarian or vegan, check with your pharmacist about the constituents of the specific brand of medicine.

No, Ofloxacin + Tinidazole is an antibiotic combination and does not have addictive properties. However, it is essential to take this medication only as prescribed by the doctor to avoid misuse or unnecessary exposure to possible side effects.

Terms & Conditions


Ofloxacin + Tinidazole in other salts

CEFIXIME + OFLOXACINCIPROFLOXACINNORFLOXACIN + TINIDAZOLEOFLOXACINOFLOXACIN + METRONIDAZOLEOFLOXACIN + ORNIDAZOLEOFLOXACIN + ORNIDAZOLE + ITRACONAZOLE + CLOBETASOLCEFPODOXIME + OFLOXACINFLUCONAZOLE + TINIDAZOLELEVOFLOXACINCLINDAMYCIN + CLOTRIMAZOLE + TINIDAZOLEAMOXICILLIN + OMEPRAZOLE + TINIDAZOLECLOBETASOL PROPIONATE + OFLOXACIN + ORNIDAZOLE + TERBINAFINECIPROFLOXACIN + CLOTRIMAZOLE + FLUOCINOLONECIPROFLOXACIN + CLOBETASOL PROPIONATE + METRONIDAZOLE + TERBINAFINEPOVIDONE IODINE + TINIDAZOLEPOVIDONE IODINE + SUCRALFATE + TINIDAZOLECLOBETASOL + OFLOXACIN + ORNIDAZOLE + TERBINAFINEDEXAMETHASONE + OFLOXACINBENZALKONIUM CHLORIDE + OFLOXACINCIPROFLOXACIN + DEXAMETHASONEBENZALKONIUM CHLORIDE + CIPROFLOXACINBENZALKONIUM CHLORIDE + CIPROFLOXACIN + DEXAMETHASONEOFLOXACIN + PREDNISOLONEBENZALKONIUM CHLORIDE + DEXAMETHASONE + OFLOXACINCEFIXIME + LACTOBACILLUS + OFLOXACINOFLOXACIN + RACECADOTRILNITAZOXANIDE + OFLOXACINOFLOXACIN + SATRANIDAZOLEOFLOXACIN + ORNIDAZOLE + RACECADOTRILKETOROLAC + OFLOXACINBETAMETHASONE + CIPROFLOXACINCIPROFLOXACIN + ORNIDAZOLECIPROFLOXACIN + TINIDAZOLECLARITHROMYCIN + LANSOPRAZOLE + TINIDAZOLEMETRONIDAZOLE + OFLOXACIN + SIMETHICONECLOTRIMAZOLE + TINIDAZOLECIPROFLOXACIN + METRONIDAZOLELACTOBACILLUS + OFLOXACINDILOXANIDE + SIMETHICONE + TINIDAZOLEAZITHROMYCIN + OFLOXACINAZITHROMYCIN + LEVOFLOXACINCEFPODOXIME PROXETIL + LEVOFLOXACINDILOXANIDE + TINIDAZOLEFLAVOXATE + OFLOXACINBALOFLOXACINCLOTRIMAZOLE + LACTOBACILLUS + TINIDAZOLEDOXYCYCLINE + TINIDAZOLELACTOBACILLUS + NORFLOXACIN + TINIDAZOLEAMBROXOL + LEVOFLOXACINLACTOBACILLUS + OFLOXACIN + ORNIDAZOLELACTOBACILLUS + LEVOFLOXACINOFLOXACIN + SODIUM CHLORIDEDEXTROSE + LEVOFLOXACIN
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