Mesterolone
Uses of Mesterolone
- Mesterolone is a synthetic androgen used to treat conditions in men caused by low testosterone levels. It belongs to the group of anabolic-androgenic steroids and is taken orally.
- Mesterolone is commonly used for:
- 1. Male hypogonadism: Treats low testosterone levels caused by the testes producing insufficient amounts of the hormone, helping to restore normal androgen levels in the body.
2. Delayed puberty in adolescent boys: Used under specialist supervision to support the development of secondary sexual characteristics in boys where puberty is significantly delayed.
3. Andropause (age-related testosterone decline): May be prescribed to manage symptoms associated with declining testosterone levels in older men, such as fatigue, reduced libido, and mood changes.
4. Male infertility due to low sperm count: Used to support sperm production in men with reduced sperm counts related to low androgen levels, as part of a fertility treatment plan.
Side effects of Mesterolone
Oily skin
Increased libido
Mood changes
Fluid retention
Changes in liver enzymes and lipid profile
How Mesterolone works
- Mesterolone is a synthetic form of the male sex hormone testosterone. It works by supplementing or replacing testosterone in men whose bodies do not produce sufficient amounts naturally.
- As an androgen, it binds to androgen receptors throughout the body and mimics the actions of naturally occurring testosterone. This helps to restore and maintain normal male physiological functions, including libido, energy levels, mood, and the development or maintenance of secondary sexual characteristics.
- It supports the hormonal environment required for healthy sperm production and maturation. Unlike some other androgens, Mesterolone is not converted to oestrogen in the body, which makes it a useful option in male fertility management where oestrogen-related side effects need to be avoided.
Certified content
Written By
Doctor of Medicine
Reviewed By
BAMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Mesterolone is administered orally and is available in the form of tablets.
Age and Dose Restrictions
Mesterolone is primarily meant for adult males of age above 18 years.
Contraindications
Mesterolone should not be used by people suffering from prostate or breast cancer.
It should also be avoided by those with severe liver disease, nephrotic syndrome, or hypercalcemia.
Other Medications to Avoid
Mesterolone may interact with insulin and oral hypoglycemic medications (such as metformin and glimepiride), anticoagulants (like warfarin), corticosteroids (such as prednisone) and other medicines causing liver toxicity (like paracetamol).
Overdose and Missed Dose
- Taking more than the prescribed dose of Mesterolone may increase the risk of serious side effects including liver toxicity (hepatotoxicity) and cardiovascular complications. If you suspect an overdose or experience symptoms such as yellowing of the skin or eyes (jaundice), severe abdominal pain, or chest discomfort, contact your doctor immediately or seek emergency medical attention.
If you miss a dose of Mesterolone, take it as soon as you remember. If it is nearly time for your next scheduled dose, skip the missed one and continue with your regular routine. Do not take a double dose to compensate for a missed one.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water may help manage side effects like fluid retention.
If you experience changes in appetite, try to eat smaller more frequent meals.
Use in Driving and Operating Machinery
Mesterolone does not generally affect your ability to drive or operate heavy machinery. However, some people may experience dizziness or fatigue. In such cases, avoid driving or operating machinery.
Use in Pregnancy and Lactation
Mesterolone should not be used by women who are pregnant as it can cause significant harm to the foetus. It should also not be taken by women who are breastfeeding.
Caution in Other Conditions
Mesterolone should be used with caution in patients with cardiovascular disease, benign prostatic hyperplasia, epilepsy, migraines, and diabetes. Regular monitoring by your doctor is advised if you have any of these conditions.
Special Dietary and Lifestyle Recommendations
Regular exercises can help maintain muscle strength and overall physical health.
Maintain a balanced diet rich in lean proteins, fruits, vegetables, and whole grains to support overall health.
Regular sleep patterns and stress management techniques may help support your mood and energy levels.
Regular check-ups with your doctor are advised to monitor your condition and adjust the dosage of Mesterolone if necessary.
Frequently asked questions
Does Mesterolone affect sleep?
Mesterolone is not associated with affecting sleep. However, it can potentially influence mood, which may indirectly affect sleep patterns. If you experience significant changes in your sleep while taking this medicine, do consult your doctor.
Can Mesterolone cause infertility?
While Mesterolone is used to manage infertility caused by low sperm count, prolonged use can suppress natural testosterone production and impair spermatogenesis, possibly reducing fertility during treatment and for some time after discontinuation.
Is it safe to take Mesterolone every day?
The safety of daily use of Mesterolone depends on the individual's health condition, age, and response to the medicine. Always follow your doctor's directions regarding the dosage and duration of treatment.
How long does it take for Mesterolone to work?
Effects of Mesterolone on libido and well-being may be noticed within a few weeks, while changes in muscle mass and body composition could take a few months.
When should I take Mesterolone?
The best time to take Mesterolone would be as directed by your doctor. It is generally taken in divided doses throughout the day.
Do I need a prescription to buy Mesterolone?
Yes, Mesterolone is a prescription medication and is not available over the counter. You should consult your doctor before starting this medication.
Is Mesterolone a steroid?
Yes, Mesterolone is a synthetic anabolic-androgenic steroid (AAS), which is a derivative of testosterone.
What is Mesterolone used for?
Mesterolone is used to treat men with low androgen levels and certain types of male infertility. By activating androgen receptors, it helps restore hormonal balance, support sexual function, and improve reproductive health.
List of medicines for Mesterolone
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