Itolizumab
Drugs For PsoriasisUses of Itolizumab
Itolizumab is a monoclonal antibody used for moderate to severe chronic plaque psoriasis in patients who are suitable for systemic treatment, according to local approval.
This medicine is commonly used for:
- Chronic plaque psoriasis: Reduces the immune activity that causes persistent thick, red, scaly plaques.
COVID-19-related cytokine release syndrome should not be presented as a routine established use.
Side effects of Itolizumab
- Itching
- Dizziness
- Diarrhoea
- Pain and swelling at the injection site
How Itolizumab works
- Itolizumab is a humanised recombinant IgG1 monoclonal antibody.
- It works by binding to a receptor called CD6 on the surface of certain immune cells called T-cells. This binding reduces the activation of these T-cells and lowers the production of inflammatory substances called cytokines.
- In chronic plaque psoriasis, this action helps reduce the skin inflammation that causes thickening, redness, and scaling.
- In COVID-19 patients with severe respiratory distress, Itolizumab helps control the cytokine storm, an excessive immune response that can worsen lung inflammation and breathing difficulty. By lowering cytokine levels, it helps ease inflammation severity and supports lung function.
Certified content
Written By
MBBS
Reviewed By
MBBS, DNB (OBGY)
Expert Advice
Dosage Forms Available
- Itolizumab is available for use via the intravenous route (Injection).
Age and Dose Restrictions
- This medicine is meant for adults and children above 18 years of age.
Contraindications
- The medication is contraindicated in patients with a known hypersensitivity to humanized recombinant IgG1 (Immunoglobulin G1) monoclonal antibody or any of its components.
Other Medications To Avoid With This Medicine
- Itolizumab may interact with live vaccines administered to infants born to female patients treated with Itolizumab during pregnancy. Before starting Itolizumab, inform your doctor about all prescription and over-the-counter medicines, as well as any vitamins and herbal supplements that you use.
Overdose and Missed Dose
- An overdose is unlikely to happen as this medicine will be given by your healthcare professional.
- If you forget to take this medicine, take it as soon as you remember. But avoid repeating the dose.
Management Of Side Effects
- Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Use In Driving And Operating Machinery
- This medicine is not known to affect your ability to drive or operate heavy machinery.
Use in Pregnancy and Lactation
- This medicine is not recommended in pregnancy or breastfeeding.
Caution In Other Conditions
- Patients with renal or hepatic conditions should exercise caution when taking this medicine.
Special Dietary & Lifestyle Recommendation
- Eat a balanced diet to keep your weight in check.
- Avoid smoking and limit alcohol intake.
- Manage stress through meditation or yoga.
- Incorporate selenium-rich foods like Brazil nuts, yellowfin tuna, beans, and spinach into your meals.
- Include zinc-rich foods such as meat, legumes, nuts, and dark chocolate in your diet.
- Reduce consumption of sugar, salt, and processed foods.
- Stay hydrated by drinking plenty of water throughout the day.
Frequently asked questions
How much time does Itolizumab take to work?
This medicine's onset of action may require a few hours to a few days for full efficacy to be realised.
What warnings and precautions should I take while taking Itolizumab?
Patients who are allergic to Itolizumab should exercise caution when taking this medication.
Can I stop taking Itolizumab if I feel healthy?
Please do not discontinue Itolizumab without consulting your doctor first. Abruptly stopping the medication may result in the return of symptoms.
Is it safe for patients with kidney or liver issues?
Patients with renal or hepatic conditions should exercise caution when taking this medicine.
Will Itolizumab affect fertility?
There is limited information on whether Itolizumab affects fertility in men or women. For the most accurate, updated details regarding this, contact your doctor.
What is the use of Itolizumab?
Itolizumab is a monoclonal antibody used in the management of moderate to severe plaque psoriasis. It modulates immune response by targeting CD6 on T-cells.
List of medicines for Itolizumab
Company
About UsHealth ArticleHealth StoriesHealth LibraryDiseases & Health ConditionsAyurvedaUnderstanding Generic MedicinesAll MedicinesAll BrandsNeed HelpFAQSecuritySavings CalculatorAdvertise with UsSubscribe
Registered Office Address
Grievance Officer
Download Truemeds
Contact Us
Our customer representative team is available 7 days a week from 9 am - 9 pm.
v4.28.18
2026 - Truemeds | All rights reserved. Our content is for informational purposes only. See additional information.
Our Payment Partners
