Hydroxyzine is an antihistamine used to relieve allergy symptoms, anxiety, and itching.
It is commonly used for:
• Allergic skin conditions: Relieves itching and hives caused by allergic reactions.
• Anxiety: Helps reduce symptoms of short-term anxiety.
• Itching (pruritus): Provides relief from generalised itching related to allergic or skin conditions.
• Pre-procedure sedation: Sometimes used to help calm and sedate patients before certain procedures.
Drowsiness
Sedation
Dizziness
Disturbed coordination
Dry mouth
Hydroxyzine works by blocking histamine, a chemical the body releases during an allergic reaction, and by acting on the central nervous system.
By blocking histamine (H1) receptors, it reduces itching, swelling, and other allergy symptoms.
Hydroxyzine also has a calming effect on the brain, which helps reduce feelings of anxiety and produces a mild sedative effect, making it useful both for allergic conditions and short-term anxiety relief.

Doctor of Medicine

BAMS, FMC, MD Resident
Hydroxyzine Hydrochloride can be taken orally (tablets, capsules, syrup and suspension) and intramuscular (infusion) routes.
This medicine is suitable for adults and children.
This medicine is contraindicated in patients with known hypersensitivity to any of the ingredients.
It is also contraindicated in patients with a prolonged QT interval.
This medicine can interact with central nervous system (CNS) depressants (e.g., benzodiazepines, alcohol), antidepressants (e.g., MAO inhibitors), muscle relaxants (e.g., carisoprodol), antihistamines (e.g., diphenhydramine), and opioids (e.g., morphine).
An overdose of Hydroxyzine Hydrochloride may cause symptoms like sedation, dizziness, seizures, nausea, and vomiting. If you suspect an overdose, it is important to seek immediate medical attention.
If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water can help manage dry mouth caused by anticholinergic effects.
Lying down in a dark, quiet room can help manage dizziness.
This medicine can affect your ability to drive or operate heavy machines. Avoid these activities if you experience dizziness or drowsiness after taking this medicine.
This medicine is not recommended during pregnancy and breastfeeding unless recommended by a healthcare professional. It is advised to consult your doctor before using this medicine during these periods.
Patients with renal or liver impairment should exercise caution while taking Hydroxyzine Hydrochloride due to its metabolism and elimination pattern.
It should also be used with caution in patients with seizure disorders, acute labyrinthitis, and the elderly due to the risk of anticholinergic side effects.
Maintain a balanced diet and regular exercise regime for overall health.
Keep yourself well-hydrated to counteract possible dry mouth side effects caused by anticholinergic properties.
Frequently asked questions
No, Hydroxyzine Hydrochloride is not a steroid. It is an antihistamine used to manage pruritus due to allergic conditions and anxiety-related disorders.
Hydroxyzine Hydrochloride is a prescription medicine and is not available over the counter.
While it is not common, some people taking Hydroxyzine Hydrochloride have reported mood changes. If you experience any significant changes in your mood, consult your doctor immediately.
Yes, Hydroxyzine Hydrochloride can cause weight gain in some individuals as a side effect, though it is not very common. If you notice significant weight changes, consult your doctor.
Hydroxyzine Hydrochloride is not considered habit-forming, and the risk of dependency is low, even with prolonged use. However, it should be used as prescribed, and any concerns about long-term use should be discussed with your doctor.
There are other antihistamines available which can be used as alternatives to Hydroxyzine Hydrochloride based on individual patient needs. However, it would be best to consult your doctor before changing your medication.
Yes, it is safe to take as prescribed by your doctor. Do not exceed the recommended dose without consulting your doctor.




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