Human Insulin/Soluble Insulin + Insulin Isophane/Nph

Dosage Forms Available

• Human Insulin/Soluble Insulin + Insulin Isophane/NPH is available in the form of a suspension for subcutaneous injection.

Age and Dose Restrictions

• The medicine is used in the management of both type 1 and type 2 diabetes in adults of age above 18 years.

Contraindications

• This medicine is contraindicated for individuals who have a known hypersensitivity to any component of Human Insulin/Soluble Insulin + Insulin Isophane/NPH.

• Additionally, it should not be used during episodes of hypoglycemia (low blood sugar).

Other Medications to Avoid

• Human Insulin/Soluble Insulin + Insulin Isophane/NPH may interact with oral antidiabetic medicines (such as metformin), corticosteroids (like prednisolone), thyroid hormones (like levothyroxine), beta-blockers (such as propranolol), ACE inhibitors (for example, lisinopril) and certain psychiatric medications (including fluoxetine and clozapine).

Overdose and Missed Dose

• Taking more insulin than prescribed can cause hypoglycaemia (low blood sugar), with symptoms such as sweating, shakiness, a fast heartbeat, hunger, blurred vision, dizziness, or tingling in the hands or feet. If you notice these symptoms, consume a fast-acting source of sugar immediately and seek medical attention if symptoms do not improve.

• If you miss a dose, take it as soon as you remember, as advised by your doctor. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• For mild injection site reactions, try applying a clean, cold compress to the area.

• Hypoglycemia can usually be managed by consuming a quick source of sugar such as glucose gel, fruit juice, or non-diet soda.

Use in Driving and Operating Machinery

• This medication can cause hypoglycemia which may affect your ability to drive or operate machinery. If you experience symptoms like dizziness, confusion, or blurred vision, avoid these activities until you feel well again.

Use in Pregnancy and Lactation

• It is recommended that you consult your doctor before using this medicine during pregnancy or while breastfeeding. Your doctor will be able to assess the risks and benefits based on your specific circumstances.

Caution in Other Conditions

• Patients with kidney or liver impairment may need to have their dose adjusted as they can be more sensitive to the glucose-lowering effect of insulin.

• Also, individuals with certain heart conditions should exercise caution when using this medication due to the potential for fluid retention.

Special Dietary and Lifestyle Recommendations

• Maintain a consistent eating schedule to help prevent hypoglycemia.

• Regular monitoring of blood glucose levels is essential for managing diabetes effectively.