Gamma Benzene Hexachloride
Uses of Gamma Benzene Hexachloride
Gamma Benzene Hexachloride (Lindane) is a topical ectoparasiticide used to treat skin infestations caused by parasites such as mites and lice.
Gamma Benzene Hexachloride is commonly used for:
• Scabies: Treats infestation by the Sarcoptes scabiei mite, which burrows into the skin and causes intense itching and a characteristic rash, particularly between the fingers, wrists, and skin folds.
• Head lice (pediculosis capitis): Eliminates lice and their eggs from the scalp and hair.
• Body lice (pediculosis corporis): Treats lice infestations affecting the body and clothing seams.
• Pubic lice (pediculosis pubis): Treats lice infestation in the genital area.
Side effects of Gamma Benzene Hexachloride
Skin irritation
Burning sensation
Itching
Rash
Dizziness
How Gamma Benzene Hexachloride works
- Gamma Benzene Hexachloride works by penetrating the outer layer of mites and lice and disrupting their nervous system, leading to paralysis and death of the parasites.
- It belongs to the organochlorine class of ectoparasiticides. When applied to the skin or scalp, Gamma Benzene Hexachloride is absorbed through the exoskeleton of mites and lice. Once inside the parasite's body, it interferes with the normal function of nerve cells by disrupting the flow of chloride ions across nerve cell membranes. This causes continuous, uncontrolled stimulation of the nervous system in the parasite.
- This overstimulation leads to convulsions, paralysis, and eventually death of the mites or lice, and may also affect their eggs to some extent. This clears the infestation and relieves associated symptoms such as itching and skin irritation.
- Because Gamma Benzene Hexachloride is applied topically and acts primarily on the parasites, it can effectively target the parasites when used as directed.
Certified content
Written By
BDS, MDS
Reviewed By
BAMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Gamma Benzene Hexachloride is available for use via topical route in the form of a 1% lotion or cream.
Age and Dose Restrictions
This medicine is intended for use in adults and in children who weigh more than 50 kg.
Contraindications
Gamma Benzene Hexachloride is contraindicated in patients with a history of seizure disorders, such as epilepsy.
It is also contraindicated in individuals with severe skin conditions that have open or crusted sores.
Other Medications to Avoid
This medicine may interact with other agents applied to the skin (such as tretinoin and hydrocortisone), certain anticonvulsant drugs for epilepsy (including phenytoin and carbamazepine), and medicines that are toxic to the nerves (like cisplatin).
Overdose and Missed Dose
- Overdose with Gamma Benzene Hexachloride is unlikely when used as directed for external application only, as it is not intended for internal use. Using more than the prescribed amount or leaving it on the skin for longer than advised may increase the risk of skin irritation or absorption-related side effects. If accidental ingestion occurs or you notice unusual symptoms such as dizziness, headache, or seizures, seek emergency medical attention immediately.
If you miss an application of Gamma Benzene Hexachloride, apply it as soon as you remember, following the prescribed schedule. Do not apply it twice or use larger amounts to compensate for a missed application. Stick closely to the application schedule advised by your doctor.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
To manage minor skin irritation or dryness, keep the affected area clean and avoid excessive washing.
If experiencing mild burning or itching, applying a cool compress to the area may help alleviate discomfort.
Use in Driving and Operating Machinery
Applying this medicine does not impair your ability to drive or operate heavy machinery. However, be cautious if you experience dizziness or sleepiness after application.
Use in Pregnancy and Lactation
Gamma Benzene Hexachloride is generally advised against during pregnancy and breastfeeding. Consult your doctor for safer alternative treatments during these periods.
Caution in Other Conditions
Patients with a history of neurological disorders should exercise caution when using this medicine due to its potential neurological effects.
Special Dietary and Lifestyle Recommendations
Maintain cleanliness of personal items such as clothing, bed linens, and towels to prevent re-infestation. Wash these items in hot water and dry them at high temperatures.
Isolate personal use items during treatment to avoid spreading the infestation to others.
Personal hygiene is crucial. Regular bathing and changing of clothing can help reduce the severity and spread of infestations.
Reduce skin-to-skin contact with others when an infestation is diagnosed until treatment has been completed successfully.
Frequently asked questions
Can Gamma Benzene Hexachloride be used for all skin conditions?
No, it is not suitable for all skin conditions. It is specifically used for managing lice and scabies infestations. It should not be applied to open sores or crusted scabby sores, as it may lead to increased absorption and a higher risk of side effects.
Is there any risk of Gamma Benzene Hexachloride causing allergies?
Yes, if you have a known allergy or past adverse reaction to it, you should avoid using it. Allergic reactions may include rash, itching, swelling, severe dizziness or trouble breathing. If any of these occur, you should seek immediate medical attention.
Will Gamma Benzene Hexachloride affect my nervous system?
It mainly affects the nervous system of mites and lice, causing their paralysis and death. However, very rarely it can also be absorbed through human skin and potentially impact the human brain and nerves in high doses.
How soon after application does Gamma Benzene Hexachloride start working?
It starts killing the mites and lice soon after application. However, it might take a few weeks for itching to completely cease even after successful treatment.
What happens if I accidentally swallow Gamma Benzene Hexachloride?
Accidental ingestion can lead to serious adverse effects such as vomiting, restlessness, convulsions, irregular heartbeat, and respiratory failure. Seek immediate medical attention in such cases.
How do I know if I am using too much Gamma Benzene Hexachloride?
Overuse or misuse can lead to serious but rare side effects such as seizures, tremors, confusion, memory loss and breathing difficulties. Always use this medication as directed by your doctor.
Are there any natural alternatives to Gamma Benzene Hexachloride?
While there are natural alternatives available that may be effective for some people, it is important to consult with a doctor before using them, as scabies, lice, and other conditions can be difficult to treat effectively.
What is Gamma Benzene Hexachloride used for?
Gamma Benzene Hexachloride (GBH), also called lindane, is used to treat scabies and lice. It kills the mites and lice causing the infestation. Available as lotions, creams, and shampoos, it is applied to the affected areas to remove pests and relieve itching.
Gamma Benzene Hexachloride in other salts
List of medicines for Gamma Benzene Hexachloride
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