Favipiravir
AntiviralUses of Favipiravir
- Favipiravir is used to treat coronavirus disease and is also prescribed for influenza, Ebola, and other viral infections. It belongs to a class of antiviral medications.
Side effects of Favipiravir
- Nausea
- Vomiting
- Abdominal pain
- Diarrhoea
How Favipiravir works
- Favipiravir selectively inhibits RNA polymerase, preventing the replication of the viral genome. Various hypotheses explain its interaction with RNA-dependent RNA polymerase (RdRp). Some studies suggest that once incorporated into a growing RNA strand, Favipiravir halts RNA elongation, thereby suppressing viral replication. Additionally, research indicates that purine analogs may reduce Favipiravir’s antiviral activity, implying competition between Favipiravir and purine nucleosides for RdRp binding.
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Written By
B. Pharm
Reviewed By
B. Pharm, MSc.
Expert Advice
Dosage Forms Available
- Favipiravir is available for use via the oral route (tablet, capsule).
Age and Dose Restrictions
- This medicine is meant for adults.
Contraindications
- The medication is not recommended in patients with a known allergy to Favipiravir and severe kidney and liver conditions.
Other Medications to Avoid
- Favipiravir may interact with anti-TB medication (pyrazinamide), blood sugar-lowering medicine (repaglinide), methylxanthines (theophylline), antiviral medicines (famciclovir, acyclovir), and NSAIDs (sulindac).
Overdose and Missed Dose
- If you accidentally overdose on this medicine, you may experience the side effects more severely. Contact your doctor immediately if you overdose.
- If you forget to take this medicine, take it as soon as you remember. But avoid repeating the dose.
Management of Side Effects
- Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Use in Driving and Operating Machinery
- This medication is not known to impair your ability to drive and operate heavy machinery.
Use in Pregnancy and Lactation
- Favipiravir is not recommended for use in pregnancy and breastfeeding unless advised by your doctor.
Caution in Other Conditions
- Patients with a history of kidney or liver issues and gout should be cautious.
Special Dietary and Lifestyle Recommendations
- Always wear a mask when around others to help prevent the spread of infection.
- Maintain social distance and avoid crowded places.
- Wash your hands frequently with soap and water or use an alcohol-based sanitizer.
- Regularly clean and disinfect frequently touched surfaces.
- Stay home and self-isolate if you feel unwell.
- Drink plenty of fluids to stay hydrated.
- Gargling with salt water and steam inhalation may provide relief.
- Engage in regular exercise, such as walking for 10 minutes in the morning, afternoon, evening, and night.
- Include protein-rich foods in your diet to support immunity and overall health.
Frequently asked questions
How much time does Favipiravir take to work?
Favipiravir starts working within a few hours of administration, but noticeable clinical improvement may take a few days, depending on the severity of the infection.
What warnings and precautions should I take while taking Favipiravir?
Avoid Favipiravir if you are pregnant or planning to conceive, as it may cause birth defects. Use contraception during and after treatment. Inform your doctor if you have gout, liver, or kidney disease.
Can I stop taking Favipiravir if I feel healthy?
No, complete the full course as prescribed by your doctor, even if you feel better, to prevent the risk of incomplete viral clearance and resistance.
Is it safe for patients with kidney or liver issues?
Patients with kidney or liver disease should use Favipiravir with caution, as it may affect organ function. Dose adjustments may be required under medical supervision.
Will Favipiravir affect fertility?
Contraceptive measures are recommended during treatment with Favipiravir and for some time after completion. Consult your doctor for guidance.
List of Medicines for Favipiravir
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