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Diastase + Pepsin


Uses of Diastase + Pepsin

  • Diastase + Pepsin combines digestive enzymes to treat dyspepsia, epigastric distress and indigestion.

Side effects of Diastase + Pepsin

  • Diarrhoea
  • Abdominal Pain
  • Feeling of sickness
  • Skin Rash

How Diastase + Pepsin works

  • Diastase, commonly known as alpha-amylase, is an enzyme derived from the controlled fermentation of fungi, particularly Aspergillus oryzae. Its primary function involves the breakdown of complex carbohydrates, such as starch, into smaller sugars, facilitating more efficient metabolism.
  • Pepsin, a potent enzyme in gastric juice, functions to digest proteins found in various food sources, including meat, eggs, seeds, and dairy products. In pancreatic insufficiency, where there is inadequate pancreatic enzyme production, pepsin is often employed as a substitute enzyme. Stimulating the pancreas for enzymatic digestion is a regulated, hormonally mediated process. Any alterations or conditions impacting the metabolic steps crucial for successful digestion and absorption can negatively influence pancreatic enzymatic secretion, its entry into the intestine, functionality within the intestine, and proper mixing with foods/nutrients. Conditions like cystic fibrosis, pancreatic cancer, acute and chronic pancreatitis, and pancreatic surgery may necessitate the initiation of enzyme replacement therapy due to pancreatic insufficiency.

Certified content

Written By

Amit SharmaClinical Health & Medical Writer| 3 Years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 12 Years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • This combination is available for use via the oral route (liquid drops and suspension, syrup).

Age and Dose Restrictions

  • This combination is meant for adults and children.


  • Diastase + Pepsin is contraindicated in patients with known allergies to diastase or pepsin.

Other Medications To Avoid With This Medicine

  • This combination may interact with anti-diabetic drugs (acarbose and miglitol).

Overdose and Missed Dose

  • Inform your doctor regarding the overdose effects of this combination and follow the advice accordingly.
  • If you forget to take this combination, take it as soon as you remember, but avoid repeating the dose.

Use In Driving And Operating Machinery

  • This combination does not affect your ability to drive or operate heavy machinery. 

Use in Pregnancy and Lactation

  • If you are expecting a baby, breastfeeding, suspect pregnancy, or have intentions of becoming pregnant, it is advisable to inform your doctor for guidance before using Diastase + Pepsin.

Special Dietary & Lifestyle Recommendation

  • Avoid alcohol when you are taking Diastase + Pepsin.
  • It is advisable to take Diastase + Pepsin before meals.

Frequently asked questions

This combination starts showing its effect within a few hours after applicationm but it may take a few weeks to show its full effect.

Avoid using this combination in the presence of an allergic reaction (hypersensitivity) to any of its components. It is advisable to seek attention from a doctor promptly.

Do not stop taking this combination without consulting your doctor, even if you feel healthy.

Consult your doctor before taking this combination if you have kidney or liver issues to ensure its safety and proper dosage.

No, there is no need to avoid any food or drinks.

Terms & Conditions

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