Cissus Quadrangularis is a herbal supplement traditionally used to support bone health and recovery after fractures.
It is commonly used for:
Clinical evidence for these benefits remains limited.
Headache
Gastrointestinal discomfort
Insomnia
Hypoglycaemia in diabetic patients

Doctor of Medicine

BAMS, FMC, MD Resident
Cissus Quadrangularis is available in various formulations for oral use. These include capsules and tablets.
Additionally, it can be found in the form of a powder that is mixed into liquids for consumption.
For topical use, it comes as a paste or gel that is applied directly to the skin.
Cissus quadrangularis is primarily used in adults. There is insufficient information regarding the safety and effectiveness of its use in children.
This medicine is contraindicated in patients with known allergies to Cissus Quadrangularis.
Also, patients with kidney stones or hypercalcaemia should avoid using this medicine.
Cissus Quadrangularis may interact with antidiabetic medicines (such as metformin, insulin, and glimepiride).
An overdose of Cissus Quadrangularis may cause symptoms such as headache, gastrointestinal discomfort, or insomnia. If you observe any of these symptoms, inform your doctor immediately.
If you miss a dose of this medicine, take it as soon as you remember. However, skip the missed dose if it is almost time for your next scheduled dose. Do not take an extra dose to make up for the missed one.
Most side effects are temporary and generally harmless and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
For headaches, rest can help. Try to avoid alcohol as it can worsen headaches.
For gastrointestinal discomfort, try to eat smaller, frequent meals rather than large ones. Avoid spicy and fatty foods.
Cissus Quadrangularis does not generally affect your ability to drive or operate machinery. However, if you experience side effects such as dizziness or sleepiness, avoid these activities until you feel normal again.
The safety of Cissus Quadrangularis during pregnancy and breastfeeding has not been fully established. Therefore, it is advisable to consult your doctor before using this medicine during these times.
Patients with diabetes should exercise caution when using Cissus Quadrangularis, as it may affect blood glucose levels.
Those with a history of kidney stones should also use this medicine with caution due to its high calcium content.
A balanced diet rich in calcium and vitamin D can support bone health.
Regular monitoring of blood glucose levels is recommended if using this medicine for managing diabetic conditions.
Frequently asked questions
Cissus Quadrangularis is a plant often used for its potential health benefits, but it is not well-documented to have significant effects on mood. Individual responses can vary, so if you notice mood changes, consult your healthcare provider.
Cissus quadrangularis has traditionally been used for skin wounds and skin-related conditions. However, there is insufficient human evidence to establish its effectiveness and safety for treating skin wounds and infections.
Cissus Quadrangularis may interfere with blood glucose levels, therefore it might affect tests related to blood sugar.
Although Cissus quadrangularis has generally been well tolerated with use for up to 10 weeks, it is advisable to consult your doctor regarding the appropriate duration of use based on your specific condition.
If you suddenly stop taking Cissus Quadrangularis, you might not experience significant withdrawal symptoms. However, any benefits you were receiving from it, such as joint support or reduced inflammation, may diminish. If you have concerns, consult your healthcare provider.
Currently, there is no scientific evidence suggesting that Cissus Quadrangularis affects mood or hormonal balance. However, individual reactions may vary so it is advisable to discuss any concerns with your doctor.
Some studies have reported reductions in body weight and body fat with certain Cissus quadrangularis extracts or combination products. However, the evidence for its benefits in weight loss is limited, and better-quality studies are needed to confirm its effects. Therefore, it should not be considered the sole approach for weight loss, but rather as a complementary measure alongside a balanced diet and regular physical activity.






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