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Cefalexin + Probenecid

Uses of Cefalexin + Probenecid

Cefalexin + Probenecid treats bacterial infections by combining a cephalosporin antibiotic with an agent that prolongs its effect in the body.
This combination is commonly used for:
• Respiratory tract infections: Treats bacterial infections such as bronchitis, pneumonia, tonsillitis, and pharyngitis.
• Skin and soft tissue infections: Clears bacterial infections affecting the skin and underlying tissue.
• Bone and joint infections: Treats bacterial infections affecting the bones and joints.
• Urinary tract infections: Manages infections such as cystitis and prostatitis caused by susceptible bacteria.
• Dental infections: Treats bacterial infections of the gums and surrounding oral tissue.

Side effects of Cefalexin + Probenecid

  • Diarrhoea
  • Nausea
  • Vomiting
  • Rash
  • Headache

How Cefalexin + Probenecid works

Cefalexin + Probenecid works through two separate mechanisms to treat bacterial infections effectively.
Cefalexin is a first-generation cephalosporin antibiotic. It inhibits the synthesis of the bacterial cell wall by binding to and inactivating proteins essential for building the cell wall. This disrupts cell wall formation and leads to bacterial death.
Probenecid is a uricosuric agent that supports Cefalexin's action. It blocks certain channels in the kidneys that would normally remove Cefalexin from the body, allowing more of the antibiotic to remain in the bloodstream for longer without increasing the dose.
Together, both medicines provide a more sustained and effective defence against susceptible bacterial infections.

Certified content

Written By

docImg
Dr. Michelle FrankMedical Content Writer| 10 years

Doctor of Medicine

Reviewed By

Dr. Osama Ahmed
Dr. Osama AhmedMedical Content Writer| 4 years

Bachelor of Dental Surgery

Expert Advice

Dosage forms available

  • Cephalexin + Probenecid is available as oral tablets to be taken by mouth.

Age and dose restrictions

  • This medication is intended for use in adults and children of age above 12 years based on body weight and clinical assessment.

Contraindications

  • Individuals with known hypersensitivity to cephalosporin antibiotics, penicillins or probenecid should not take Cephalexin + Probenecid.
  • It is also contraindicated in patients diagnosed with carcinoid syndrome.

Other medications to avoid

  • Cephalexin + Probenecid may interact with NSAIDs (like ibuprofen and naproxen), aminoglycosides (like gentamicin and amikacin), tetracyclines (such as doxycycline and minocycline), macrolides (like erythromycin and azithromycin).

Overdose and missed dose

  • Taking more than the prescribed dose may cause nausea, vomiting, epigastric distress, and diarrhoea. If you suspect an overdose, seek medical attention immediately.
  • If you miss a dose of Cefalexin + Probenecid, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose to avoid a potential overdose. Completing the full prescribed course is important to prevent the infection from returning or becoming resistant to antibiotics.

Management of side effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of water can reduce potential gastrointestinal side effects like diarrhoea or nausea.
  • Ensuring ample rest may help manage fatigue or dizziness.

Use in driving and operating machinery

  • As some people may experience dizziness or fatigue, caution is advised when driving or operating heavy machinery after taking Cephalexin + Probenecid.

Use in pregnancy and lactation

  • It is recommended to consult a doctor before using this medication during these periods.

Caution in other conditions

  • Patients with kidney impairment should exercise caution and may require dose adjustments when taking Cephalexin + Probenecid.
  • Persistent diarrhoea may be a sign of Clostridium difficile-associated diarrhoea, and the medicine should be discontinued and a doctor consulted.

Special dietary and lifestyle recommendations

  • Maintaining good personal hygiene can help prevent further bacterial infections.
  • Regular hand washing can help reduce the risk of spreading infection to others.
  • It's recommended to avoid close contact with others who have bacterial infections, if possible.
  • A balanced diet rich in vitamins and minerals can support the immune system in fighting off infections.

Frequently asked questions

No, Cephalexin + Probenecid is not a steroid. It is a combination of two active ingredients Cefalexin, a first-generation cephalosporin antibiotic, and Probenecid, a uricosuric agent.

Cephalexin + Probenecid is not associated with affecting sleep. However, if you have any concerns about this, you should discuss them with your doctor.

Cephalexin + Probenecid is not directly associated with affecting fertility. However, if you are planning to conceive, you should discuss this with your doctor.

The safety of daily consumption of Cephalexin + Probenecid depends on the duration and dosage prescribed by your doctor. The medicine is taken as advised by your doctor based on the type and severity of the infection.

Cefalexin, one of the components of the combination, reaches peak levels in the body 1-2 hours after an oral dose. The time it takes to start working can vary depending on the type of infection and individual patient factors.

Cephalexin + Probenecid can be taken with or without food. The best time to take this medicine would be as prescribed by your doctor, usually every 12 hours.

It is best to consult your doctor for alternatives to Cephalexin + Probenecid as different salts may work differently and their effect on your condition would depend on various factors like the severity and type of infection.

Terms & Conditions


Cefalexin + Probenecid in other salts

List of medicines for Cefalexin + Probenecid

Alcephin La 500/500 Mg Tablet 10
Alcephin La 500/500 Mg Tablet 10
Alembic Pharmaceuticals Ltd
Pack of 10 Units
₹84.49
MRP ₹105.61
20% OFF
Ceff La 250/250 Mg Tablet 10
Ceff La 250/250 Mg Tablet 10
Lupin Ltd
Pack of 10 Units
₹69
MRP ₹86.25
20% OFF
Unifex 250/250 Mg Tablet 10
Unifex 250/250 Mg Tablet 10
Bestochem Formulations (I) Ltd
Pack of 10 Units
₹57.14
MRP ₹71.42
20% OFF
Ceff-La 500/500 Mg Tablet 10
Ceff-La 500/500 Mg Tablet 10
Lupin Ltd
Pack of 10 Units
₹139.22
MRP ₹174.03
20% OFF
Alcephin La 250/250 MG Tablet 10
Alcephin La 250/250 MG Tablet 10
Alembic Pharmaceuticals Ltd
Pack of 10 Units
₹49.98
MRP ₹62.48
20% OFF
Unifex 500/500Mg Capsule 10
Unifex 500/500Mg Capsule 10
Bestochem Formulations (I) Ltd
Pack of 10 Units
₹57.14
MRP ₹71.42
20% OFF
Unifex Forte 500/250 Mg Tablet 6
Unifex Forte 500/250 Mg Tablet 6
Bestochem Formulations (I) Ltd
Pack of 6 Units
₹56.76
MRP ₹70.95
20% OFF
Unifex Forte 500/250 Mg Capsule 10
Unifex Forte 500/250 Mg Capsule 10
Bestochem Formulations (I) Ltd
Pack of 10 Units
₹71.94
MRP ₹89.92
20% OFF

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