Carica Papaya (papaya leaf extract) is a natural plant-based preparation used primarily as supportive therapy in conditions associated with low platelet counts.
Carica Papaya is commonly used for:
• Dengue fever (thrombocytopaenia): Papaya leaf extract is widely used as a supportive treatment and may help support platelet counts in people with dengue fever.
• Low platelet count (thrombocytopaenia): Used to support platelet production in patients with reduced platelets due to various causes.
• Digestive health: The natural enzymes in papaya, including papain and chymopapain, support digestion by helping to break down proteins, easing bloating and digestive discomfort.
• Liver support: May help protect cells from oxidative stress due to its antioxidant properties.
• Skin health: Applied topically, papaya-derived enzymes have been used to gently exfoliate skin and support wound healing.
• Anti-inflammatory support: The phytochemicals in papaya leaves have antioxidant and anti-inflammatory properties that may support overall health.
Allergic reactions
Stomach irritation
Carica Papaya works through the action of its naturally occurring bioactive compounds, including enzymes, flavonoids, alkaloids, tannins, and saponins.
The key mechanisms include:

Doctor of Medicine

BAMS, FMC, MD Resident
Carica Papaya is available for consumption in several forms including fresh fruit, juice, tea made from the leaves, and dietary supplements in the form of capsules or tablets.
Carica Papaya is generally safe for adults and children. However, the dosage and form of intake may vary depending on the age and health condition of the person. It is advisable to consult a doctor for appropriate dosage and intake methods.
Consumption of Carica Papaya is contraindicated in individuals who are allergic to any component of the papaya plant, including its fruit, leaves, or latex.
It is also contraindicated for those with a history of hypoglycemia as it may further lower blood sugar levels.
Carica Papaya may interact with anticoagulants (such as warfarin), antiplatelet medications (like clopidogrel), and diabetes medications (such as metformin).
If you miss a dose of Carica Papaya extract, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to compensate for the missed one.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
For skin irritation or rashes, discontinue use and consult with your doctor.
If you experience stomach upset or diarrhoea, consider taking the medicine with food.
Carica Papaya does not interfere with your ability to drive or operate machinery. It has no known side effects that might cause dizziness or drowsiness.
Unripe Carica Papaya fruit might cause uterine contractions in pregnant women. It is best to consult with your doctor before consuming Carica Papaya during pregnancy or while breastfeeding.
Individuals with diabetes should monitor their blood sugar levels closely when consuming Carica Papaya as it might lower blood sugar.
People with heart conditions who are taking medications like warfarin should also exercise caution, as Carica Papaya may enhance the effects of these medicines, leading to increased bleeding risks.
Maintain a healthy diet rich in fruits, vegetables, and lean proteins.
Drink plenty of water to stay hydrated and aid digestion.
Frequently asked questions
Yes, Carica papaya is beneficial for skin health. It contains enzymes like papain, vitamins A and C, and antioxidants that help exfoliate, hydrate, and reduce inflammation, promoting healthy and glowing skin.
Indeed, Carica Papaya contains an enzyme called papain that aids in the digestion of proteins. It also has a mild laxative effect, promoting regular bowel movements. Therefore, consuming Carica Papaya can support digestive health.
Yes, Carica Papaya is beneficial for cardiovascular health. It contains dietary fibre and potassium that help regulate blood pressure levels. The fibre also binds with cholesterol in the gut and prevents its absorption, thus improving lipid profiles.
Yes, Carica Papaya is rich in anti-inflammatory compounds like papain and chymopapain, which help reduce inflammation in the body. This is beneficial in managing conditions like arthritis and asthma.
In vitro, studies suggest that papaya leaf extract may have potential anticancer effects by inhibiting the growth of different cancer cell lines and inducing apoptosis or programmed cell death in cancer cells. However, more research is needed to establish these effects in humans.
Be cautious if you're allergic, pregnant, or taking medications that might interact.
While certain studies suggest that Carica Papaya leaf extract has demonstrated antiviral activity against viruses like dengue and chikungunya, more research is necessary to support this use.






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