Carboprost

Dosage Forms Available

• Carboprost can be administered via the intramuscular route (injectable solution).

Age and Dose Restrictions

• This medicine is intended for use by women of reproductive age.

Contraindications

• Patients with known hypersensitivity to Carboprost or other prostaglandins, as well as those with active cardiac, pulmonary, renal, or liver disease, should not use this medication. It is also contraindicated for individuals with a history of stroke or seizure disorders and should not be used by those with uncontrolled hypertension.

Other Medications to Avoid

• Carboprost can interact with oxytocic medicines (e.g., oxytocin and ergot alkaloids), antihypertensives (e.g., lisinopril, amlodipine), and anti-inflammatory medicines (e.g., aspirin, ibuprofen).

Overdose and Missed Dose

• Overdose of Carboprost may lead to severe side effects such as excessive uterine tone, decreased uterine blood flow, dizziness, or severe abdominal pain. If you suspect an overdose, you should contact your doctor immediately.

• If you miss a dose of this medication, consult your doctor for further instructions. Never double up on doses to compensate for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing Carboprost. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of fluids can help manage gastrointestinal symptoms like nausea and diarrhoea.

• Resting in a quiet, dark room may help manage headaches.

Use in Driving and Operating Machinery

• Carboprost may cause dizziness or confusion. Patients should avoid driving or operating heavy machinery if they experience these side effects after receiving this medication.

Use in Pregnancy and Lactation

• It is crucial to consult a doctor before using Carboprost during pregnancy and lactation as it can induce uterine contractions and potentially lead to abortion or premature birth.

Caution in Other Conditions

• Caution is advised in patients with a history of heart problems, asthma, hypertension, kidney and liver disease, jaundice, anaemia, and diabetes.

Special Dietary and Lifestyle Recommendations

• Regularly check your blood pressure, especially if you have a history of hypertension, as Carboprost can potentially raise blood pressure.

• Opt for a bland, low-fiber diet to minimise gastrointestinal irritation and manage symptoms like nausea and vomiting.

• Limit strenuous physical activities immediately following the injection to avoid exacerbating side effects such as severe uterine contractions.