Abacavir + Lamivudine

Dosage Forms Available

• Abacavir + Lamivudine is available as tablets meant for oral administration.

Age and Dose Restrictions

• This medicine is designed for use by adults and children over the age of 12 who weigh at least 25 kg.

Contraindications

• Abacavir + Lamivudine is contraindicated in patients who have had a prior hypersensitivity reaction to either abacavir or lamivudine.

• Patients who test positive for the HLA-B*5701 allele should not be prescribed this medication.

Other Medications to Avoid

• Abacavir + Lamivudine may interact with other antiretrovirals (such as emtricitabine), vasodilators used for pulmonary hypertension (like riociguat), antiviral medicines (such as ribavirin) and opioid medications (including methadone).

Overdose and Missed Dose

• Taking more than the prescribed dose may cause serious effects such as a build-up of lactic acid in the body or liver problems. If you suspect an overdose, seek medical attention immediately.

• If you miss a dose of Abacavir + Lamivudine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Nausea and vomiting can be managed by taking the medication with food.

• Fatigue may be managed by ensuring you get enough rest and sleep.

• Headaches can be managed by staying hydrated and resting in a quiet, dark room.

Use in Driving and Operating Machinery

• Abacavir + Lamivudine may cause dizziness or fatigue. If you feel dizzy or tired after taking this medicine, avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

• The use of Abacavir + Lamivudine during pregnancy should be discussed with your doctor to weigh the potential benefits against the potential risks to the foetus.

• Consult your doctor before using this medicine during breastfeeding.

Caution in Other Conditions

• Patients with kidney problems may need dose adjustments when using Abacavir + Lamivudine.

• Patients with liver disease, hepatitis B or C co-infection, or risk factors for liver disease should use this medication with caution.

Special Dietary and Lifestyle Recommendations

• Eating a balanced diet can help boost the immune system and manage HIV infection.

• Practising safe sex can help prevent the spread of HIV to others.

• Regular health check-ups are necessary to monitor your condition and adjust your medication as needed.